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How to sell supplements: web shop, Amazon, practices, direct selling and more

Reviewed by Dr. Daniel Wallerstorfer, molecular biologist and founder of Novogenia · Updated: 11 October 2026 · Reading time: 8 min

In short

There are six typical supplement sales channels: your own web shop, marketplaces, practices and advisors, pharmacies and drugstores, direct selling and B2B sales to companies. Each channel places its own demands on margin, packaging, logistics and marketing. One rule applies to all of them: in the EU, health-related marketing claims are only permitted if they have been authorized.

Why you should decide on your sales channel early

When founders plan their own supplement, they usually think about the formula first. But the sales channel determines almost everything that follows: pack size, packaging, retail price, margin, launch volume and how you explain your product. A product for pharmacies needs different packaging than one for direct selling; a product for your own web shop needs a different pricing strategy than one for a marketplace.

So settle on your sales channel at the concept stage – before you design the packaging and order your first volume.

Your price has to fit the channel

Work backward from the retail price. Depending on the channel, different costs come out of what your customer pays:

If too little is left after that, either the channel or the price does not fit. How manufacturing costs are made up is explained in What does contract manufacturing cost?

Supplement sales channels compared

Sales channelAdvantagesDisadvantagesGood fit for
Own web shopfull margin, your own customer data, subscriptions easy to set upyou have to attract visitors yourself; payment, shipping and service are on youbrands with reach, a community or an advertising budget
Marketplaceslarge reach, customers trust the platformtheir own rules and approvals, fees, strong price comparison, little customer dataproducts with clear search demand
Practices and advisorshigh trust, personal recommendationlimited volume per practice, professional rules to observeproducts that need explaining, personalized products
Pharmacies and drugstorescredibility, walk-in customersretail margin, hard for new brands to get listed, printed packaging neededestablished brands, retailers’ own brands
Direct sellingpersonal recommendation, recurring demandcommissions, responsibility for what partners sayproducts taken every day
B2B and corporate healthlarger volumes per customerlong decision processes, a few large customerscompanies, gyms, institutions

Your own web shop

In your own shop, you own the entire customer relationship: you know who your buyers are, you can reach out to them again and you can offer a subscription with automatic reorder. No retailer takes a cut, so the margin stays with you.

The price for that: you have to attract visitors yourself – through advertising, content, social media or an existing community. On top of that come payment processing, shipping, customer service and the legal obligations of running an online shop. Check the rules for e-commerce in your target market.

Tip: your shop is the natural home for a subscription. How to build predictable revenue with one is covered in Subscription models.

Marketplaces such as Amazon

Marketplaces bring reach that a new shop would first have to build. Customers search there for specific products and trust the platform with payment and delivery.

In return, the marketplace’s rules apply. Marketplaces have their own requirements for supplements, sometimes with approval processes and documentation requirements, and these can change. So check the current conditions before you plan your packaging and launch volume. Other points to consider:

Practices, therapists and advisors

Doctors, naturopaths, nutritionists, physiotherapists and trainers enjoy their clients’ trust. A recommendation made during a consultation carries more weight than any ad. That makes this channel ideal for products that need explaining – and especially for personalized supplements, where genetic or blood data are discussed.

Two points to be aware of:

A model that often works well for practices: the practice recommends, and the product is shipped directly to the client – with no stock held in the practice.

Pharmacies and drugstores

In retail, you benefit from credibility and walk-in customers. For new brands, however, getting onto the shelf is demanding: retailers want a share of every sale, supply often runs through wholesalers, and to get listed you need convincing arguments – such as proven demand from your own shop.

For retail, you usually need fully printed packaging with a barcode and pricing that can carry the retail margin. More on packaging options in Packaging.

The reverse route is also possible: pharmacies and drugstores that build their own brand and are looking for a contract manufacturer.

Direct selling and network marketing

In direct selling, independent sales partners recommend your product within their own networks. Supplements are a good fit because they are taken every day and reordered regularly – ideally, every customer won brings recurring revenue.

B2B and corporate health

Companies buy supplements too – for example as an offer for employees as part of workplace health programs. Other B2B customers can include gyms, hotels or institutions that want to offer a product under their own brand.

The advantage: larger volumes per customer. The disadvantage: long decision processes, tenders and a heavy dependence on a few buyers. Have tax and employment-law questions about employee offers checked in the country concerned.

Logistics: who ships your products?

Your sales channel also determines how your products reach your customers:

OptionHow it worksA good fit if …
Delivery to your warehouseThe manufacturer delivers the finished goods to you, and you ship them yourself.you already have a warehouse or supply retailers.
External fulfillment providerA logistics company stores, packs and ships for you.you sell large volumes across several channels.
Manufacturer as fulfillment partnerThe manufacturer ships directly to your end customers, under your brand.you don’t want a warehouse, offer a subscription or sell personalized products.

With personalized products, direct shipping is almost a must: every box is produced for one specific person, so an intermediate warehouse offers no advantage.

Marketing: the rules apply in every channel

Whether in your shop, on a marketplace, in a consultation or in a sales partner’s post: in the EU, health-related statements about a supplement are only permitted if they have been authorized. Promises to cure are, as a rule, off-limits for foods. Which wording is allowed is explained in Health claims: what you may advertise.

Responsibility lies with whoever sells the product under their own name. So build a collection of reviewed statements early on, for use across all channels and by all partners.

Combining channels: a checklist

Most brands start with one channel, get to know their target group and then add more. Keep prices and messaging consistent so that your channels don’t undermine one another.

Frequently asked questions

Where can I sell supplements?
The main supplement sales channels are your own web shop, marketplaces, practices and advisors, pharmacies and drugstores, direct selling and B2B customers such as companies. Which one fits depends on your target group, your margin and how much explanation your product needs. Many brands start with one channel and add more later.
What do I need to have in place before my first sale?
Whoever sells a supplement under their own name is responsible for the product and its labeling. Many EU countries require a notification – in Germany, for example, to the BVL at the latest when the product is first placed on the market; Austria provides for none. Retailers and marketplaces may also require their own documentation. At Novogenia, we handle the notification in most cases or guide you through it.
Can I sell supplements on Amazon?
In principle, yes – but marketplaces have their own rules for supplements, sometimes including approval processes and documentation requirements, and these can change. Check the marketplace’s current requirements before you plan your packaging and launch volume, and make sure your listing copy only contains authorized health claims.
Is direct selling a good fit for supplements?
Yes, because supplements are used daily and reordered regularly. Keep in mind: as the brand, you are also responsible for what your sales partners say about the product. So train them on which statements are permitted and give them reviewed copy to use.
Can Novogenia ship directly to my customers?
Yes. Novogenia can ship directly to your customers as your fulfillment partner, under your brand. Billing runs via Novogenia or via your own system. That way, you don’t need a warehouse of your own to launch.

Related: Subscription models: recurring revenue · Health claims: what you may advertise · White label: personalized supplements

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