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Combining cosmetics and supplements: skincare from outside, nutrients from inside

Reviewed by Dr. Daniel Wallerstorfer, molecular biologist and founder of Novogenia · Updated: 13 October 2026 · Reading time: 10 min

In short

Skin can be supported from two sides: with skincare from the outside and with nutrients from the inside. At Novogenia, both products come from one saliva sample – day serum, night serum and body lotion from the cosmetics factory, personalized supplements from the supplement factory in the same building. Legally, they remain two worlds: cosmetics follow Regulation (EC) No 1223/2009, supplements follow food law with its authorized health claims. For skin, such claims exist, for example “Zinc contributes to the maintenance of normal skin.” Use them in their official wording and only for the supplement.

Two routes to the skin

Researchers analyzed data from 4,025 women aged 40 to 74 from a large US health survey. Dermatologists had examined their skin, and their diet over the previous 24 hours was recorded. The result: women with higher vitamin C intakes from food were less likely to have a wrinkled appearance and less likely to have age-related skin dryness. Higher linoleic acid intakes were also linked to less age-related dryness. These associations held after the researchers accounted for age, sun exposure, body weight and other factors (Cosgrove et al., American Journal of Clinical Nutrition, 2007).

A review from New Zealand explains why vitamin C in particular is so closely tied to skin: normal skin contains high concentrations of it, and it stimulates collagen formation and assists antioxidant protection against light damage. The authors compare both routes – supply through the diet and application to the skin (Pullar et al., Nutrients, 2017).

From this, a simple picture emerges: the skin has two entrances. Skincare reaches it from the outside, and nutrients from food and supplements reach it from the inside. An offer that uses both entrances is closer to how skin really works. Just do not mix up one thing: an observational study on diet is not an efficacy promise for a product. What you may advertise is governed by law – separately for each entrance.

One saliva sample, two products

At Novogenia, both start with the same saliva sample. The lab analyzes it in 4 days. A gene only makes it into the analysis if at least three independent studies support its effect. Two products come from the result:

Both adjustments are logical conclusions from the genetic profile. The genetic traits themselves are well documented. That a formula derived from them has a specific effect has not been confirmed in dedicated studies for every gene. Say so openly – it makes your offer more credible, not weaker. How genes become skincare is shown in Personalized cosmetics.

Serum and supplement may sit in the same package, but legally they belong to different worlds:

QuestionCosmetics: serum and lotionFood supplement
What it issubstances or mixtures placed in contact with external parts of the body such as the skin, to clean them, protect them, change their appearance or keep them in good condition (Regulation (EC) No 1223/2009, Article 2)foods intended to supplement the normal diet (Directive 2002/46/EC)
Before saleresponsible person (Article 4), safety assessment with safety report (Article 10), product information file (Article 11), electronic notification to the European Commission (Article 13)depending on the country, a notification to the authority
Claimsno implied characteristics or functions the product lacks (Article 20); six common criteria of Regulation (EU) No 655/2013only authorized health claims (Regulation (EC) No 1924/2006)
At NovogeniaNovogenia takes on the role of responsible person; manufacturing to ISO 22716manufacturing under ISO 22000:2018; in most cases Novogenia handles the notification or supports you with it

The six criteria for cosmetic claims are: legal compliance, truthfulness, evidential support, honesty, fairness and informed decision-making. More in Advertising cosmetics and Responsible person, safety assessment, notification.

Which skin topics can be supported from the inside

For skincare from the outside, every topic of the skin analysis helps decide which active ingredients go into the day serum, night serum and body lotion, and at what dosage. For supplements from the inside, the question is different: is there an authorized claim for the matching nutrient?

Topic of the skin analysisNutrients with an authorized claimGood to know
Collagen breakdown (MMP1) and collagen productionvitamin C (collagen formation for the normal function of skin)Gene story: Collagen production
Oxidative stress (SOD2, GPX1, NQO1)vitamin C, vitamin E, selenium, zinc, copper, riboflavin, manganese (protection of cells from oxidative stress)Gene story: Oxidative stress
Selenium (GPX1)selenium (protection of cells from oxidative stress; maintenance of normal hair and nails)Gene story: Selenium
Coenzyme Q10 (NQO1)none: the list of authorized claims has no entry for coenzyme Q10offer it without health-related advertising
Hydrationno specific claim; general skin claims exist for biotin, niacin, vitamin A and zinc, for examplehydration is mainly a topic for skincare from the outside
Tendency toward inflammation (TNF-α, IL6)no suitable claimstatements about inflammation belong in no advertising
UV protection (MC1R)noneNeither skincare nor supplements replace sun protection.

The authorized health claims for skin, word for word

The list of authorized health claims is set out in Regulation (EU) No 432/2012. For skin, the consolidated version of 20 August 2025 reads:

NutrientAuthorized claim
Biotin“Biotin contributes to the maintenance of normal skin”
Iodine“Iodine contributes to the maintenance of normal skin”
Niacin“Niacin contributes to the maintenance of normal skin”
Riboflavin (vitamin B2)“Riboflavin contributes to the maintenance of normal skin”
Vitamin A“Vitamin A contributes to the maintenance of normal skin”
Zinc“Zinc contributes to the maintenance of normal skin”
Vitamin C“Vitamin C contributes to normal collagen formation for the normal function of skin”
Copper“Copper contributes to normal skin pigmentation”

For oxidative stress, there are claims such as “Selenium contributes to the protection of cells from oxidative stress,” in the same form for vitamin C, vitamin E, zinc, copper, riboflavin and manganese. For hair, there is for example “Biotin contributes to the maintenance of normal hair.” Three rules keep you on the safe side:

All rules for food advertising are explained in Health claims: what you may advertise in the contract manufacturing guide.

Well phrased: examples for a combined offer

BetterProblematicWhy
“Zinc contributes to the maintenance of normal skin.” (for the supplement)“Inside and out against skin aging”an anti-aging promise that goes beyond the authorized claim
“Vitamin C contributes to normal collagen formation for the normal function of skin.” (for the supplement)“The serum with vitamin C boosts your collagen production.”transfers the food claim to a cosmetic; an efficacy claim about the serum needs its own evidence
“Which active ingredients go into your serum, and at what dosage, depends on your genes.*”“The serum makes up for your defective genes.”cosmetics do not change genes; the formula is a logical conclusion
“Selenium contributes to the protection of cells from oxidative stress.”“Selenium protects your skin from inflammation.”disease-related and not authorized in this form

* With a note: the genetic traits are backed by studies; the formula derived from them is a logical conclusion, not scientifically proven.

From a single source: supplements and cosmetics under one roof

Two products do not mean two suppliers. In Eugendorf near Salzburg, the genetic lab, the supplement factory and the cosmetics factory share one building; the personalized cosmetics are formulated and filled separately in our own cosmetics production. For you, this means:

How personalized supplements are made is described in the contract manufacturing guide, for example in Manufacturing personalized supplements. The offer at a glance: White label for personalized supplements and cosmetics.

How to build a combined offer

FormatContentRhythm
Skincare starterskin analysis, results conversation, day serum, night serum and body lotionone-off, with reorders
Outside and insideplus personalized supplementssupplements every 90 days
Subscription with check-inboth products, plus a regular consultationquarterly, matching the 90-day delivery

The table is a model, not a fixed package list. The combination is especially natural in spas and wellness hotels: the skincare is part of the treatment, and the supplements follow as a takeaway or subscription after the stay (Selling cosmetics). Start small: white-label cosmetics are available from small batches, supplements from a single unit. How to plan recurring orders is shown in Subscription models.

Checklist: combining cosmetics and supplements

Frequently asked questions

May I advertise a supplement with skin-related claims?
Yes, with an authorized health claim, for example “Biotin contributes to the maintenance of normal skin.” The condition: the product is at least a source of the nutrient as defined in the Annex to Regulation (EC) No 1924/2006. Claims that a product prevents, treats or cures skin diseases are prohibited.
May I use the health claims for the serum as well?
No. The authorized claims of Regulation (EU) No 432/2012 apply to foods, including food supplements. Cosmetics are governed by the Cosmetics Regulation: claims must not imply characteristics or functions the product does not have (Article 20 of Regulation (EC) No 1223/2009), and they must meet the common criteria of Regulation (EU) No 655/2013. If both products contain the same nutrient, each needs its own, suitable claim.
Can a supplement be a cosmetic product?
No. A cosmetic product is intended to be placed in contact with external parts of the body such as the skin (Article 2(1)(a) of Regulation (EC) No 1223/2009). Anything meant to be swallowed is not a cosmetic – even if the pack says “beauty.” Food supplements are governed by food law.
Do I need two manufacturers for cosmetics and supplements?
Not with Novogenia. The genetic lab, the supplement factory and the cosmetics factory are in the same building in Eugendorf near Salzburg, and both products are available as white label under your brand. The cosmetics are formulated separately in our own cosmetics production.
Does the genetic analysis shape both formulas in the same way?
No. For the day serum, night serum and body lotion, the genetic result determines the selection and dosage of the active ingredients. For the supplement, a questionnaire and, where available, blood values are used alongside the genes. Both adjustments are logical conclusions from the genetic profile, not scientifically proven.

Related: White label: personalized supplements and cosmetics · Health claims: what you may advertise · Advertising cosmetics: what is allowed

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